Production and Characteristics of Avicel-Digesting and Non-Avicel-Digesting Cellobiohydrolases from Aspergillus ficum

Production and Characteristics of Raw-Starch-Digesting alpha-Amylase from a Protease-Negative Aspergillus ficum Mutant.

Mutational experiments were carried out to decrease the protease productivity of Aspergillus ficum IFO 4320 by using N-methyl-N'-nitro-N-nitrosoguanidine. A protease-negative mutant, M-33, exhibited higher alpha-amylaseactivity than the parent strain under submerged culture at 30 degrees C for 24 h. About 70% of the total alpha-amylase activity in the M-33 culture filtrate was adsorbed onto sta...

Digesting GWAS

nce upon a time, medical genetics was a relaOtively straightforward business: one gene—one protein—one disease was sufficient to explain most inherited disease and was neatly in keeping with Gregor Mendel’s discovery of alleles with his famous peas. The concept remains a good starting point but the biology of life is somewhat more complex, and increasingly we have become impressed and perplexed...

Digesting dietary miRNA therapeutics

Hippocrates famously advised, " Let food be thy medicine and thy medicine be thy food. " Numerous plant-derived compounds are used as cancer therapeutics including antimitotics, topoisomerase inhibitors, and kinase inhibitors. Here we will review emerging evidence suggesting that diet derived small RNAs may be an inexpenisive, non-invasive and affordable way to deliver cancer treatments. RNA in...

Studies of Agar-digesting Bacteria.

Production and characterization of pellets using Avicel CL611 as spheronization aid.

PURPOSE The study looked into the feasibility of producing pellet using Avicel CL611 as spheronization aid by the extrusion/spheronization technique. METHODS Pellets were formulated to contain either 20% or 40% Avicel CL611 and lactose monohydrate as the other sole ingredient. Water is used as liquid binder. Quality of pellets and extrudates were analyzed for size distribution, shape, surface...